Fri Mar 08 2024

38 articles - From Friday Mar 01 2024 to Friday Mar 08 2024

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Guidelines

Guidelines and related publications, position statements, white papers, technical reviews, consensus statements, etc…

Pancreatology

Guideline adherence in acute pancreatitis: Still a long way to go.

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Meta-analysis

meta-analyses and systematic reviews

Am J Clin Nutr

Dosage exploration of combined B-vitamin supplementation in stroke prevention: a meta-analysis and systematic review.

Our meta-analysis found that the folic acid combined with vitamin B12 and vitamin B6 supplementation strategy significantly reduced the risk of stroke in areas without and with partial folic acid fortification. Combined dosages not exceeding 0.8 mg/d for folic acid and 0.4 mg/d for vitamin B12 supplementation may be more effective for populations within these areas.

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Inflamm Bowel Dis

Dietary Interventions and Supplementation in Patients With an Ileal Pouch-Anal Anastomosis: A Systematic Review.

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Risk of Infection in Patients With Inflammatory Bowel Disease Treated With Interleukin-Targeting Agents: A Systematic Review and Meta-Analysis.

There was no difference in risk of infection between patients with IBD who received IL-targeting agents compared with the control group. Case registries and randomized controlled trials reporting the safety of IL inhibitors should provide detailed information about the risk of specific infectious complications in patients with IBD receiving IL-targeting agents.

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Original articles

RCT, clinical trials, retrospective studies, etc…

Am J Clin Nutr

Associations between dietary indices and hearing status among middle-older aged adults- Results from the Baltimore Longitudinal Study of Aging.

Adherence to healthy dietary patterns was associated with better hearing status, with stronger associations at high frequencies.

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Associations between sodium, potassium, and blood pressure: Results from the Hispanic Community Health Study/Study of Latinos, a prospective cohort study.

Among a large sample of diverse US Hispanics/Latino adults, higher sodium intake was associated with small increases in systolic blood pressure over six years. This research underscores the importance of dietary sodium reduction in maintaining lower blood pressure.

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Biomarker-assessed total energy intake and its cohort study association with all-cause mortality in postmenopausal females.

Lower EI is associated with lower all-cause mortality among younger postmenopausal females with stable or increasing weight, and with higher mortality risk among older females with weight loss. This study is registered with clinicaltrials.gov identifier NCT00000611.

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Birth Outcomes in Relation to Neighborhood Food Access and Individual Food Insecurity During Pregnancy in the Environmental influences on Child Health Outcomes (ECHO)-Wide Cohort Study.

Residence in LILA or LILV neighborhoods during pregnancy is associated with adverse birth outcomes. These findings highlight the need for future studies examining whether investing in neighborhood resources to improve food access during pregnancy would promote equitable birth outcomes.

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Changes in Bile Acid Subtypes and Improvements in Lipid Metabolism and Atherosclerotic Cardiovascular Disease Risk: The POUNDS Lost trial.

Decreases in distinct BA subtypes were associated with improved lipid profiles and ASCVD risk estimates, highlighting the importance of changes in circulating BA subtypes as significant factors linked to improved lipid metabolism and ASCVD risk estimates in response to weight-loss dietary interventions. Habitual dietary fat intake may modify the associations of changes in BAs with ASCVD risk.

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Chronic and postprandial effect of blueberries on cognitive function, alertness, and mood in participants with metabolic syndrome - results from a six-month, double-blind, randomized controlled trial.

Although self-rated calmness improved postprandially, and significant cognition-metabolite associations were identified, our data did not support strong cognitive, mood, alertness, or sleep quality improvements in MetS participants after blueberry intervention.

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Contribution of baby food pouches and other commercial infant foods to the diets of infants: a cross-sectional study.

Baby food pouches make relatively small contributions to energy intake in infants, but are important sources of carbohydrate, fiber, and vitamins A, C and B6. Almost half of the total sugars consumed from complementary foods is provided by these pouches. Clinical trial registry Australian New Zealand Clinical Trials Registry (registration number ACTRN12620000459921; website for the FFNZ study.

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Cost-effectiveness of teduglutide in adult patients with short bowel syndrome - a European socioeconomic perspective.

Teduglutide in treating SBS-IF patients meets the traditional cost-effectiveness criteria from a European societal perspective. Nevertheless, the varying levels of teduglutide efficacy leave a degree of uncertainty to the calculations.

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Creatine and pregnancy outcomes: a prospective cohort study of creatine metabolism in low-risk pregnant females.

Although maternal plasma creatine concentrations were highly conserved, creatine metabolism appears to adjust throughout pregnancy. An ability to maintain creatine concentrations through diet and shifts in endogenous synthesis may impact fetal growth.

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Effect of 1-year lifestyle intervention with energy-reduced Mediterranean diet and physical activity promotion on the gut metabolome and microbiota: a randomized clinical trial.

An intervention based on an energy-reduced MedDiet and physical activity promotion, compared with an ad libitum MedDiet, was associated with improvements in cardiometabolic risk factors, potentially through modulation of the fecal microbiota and metabolome. Clinical trial registry number ISRCTN89898870 (

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Excluding whole grain containing foods from the Nova ultra-processed food category: a cross-sectional analysis of the impact on associations with cardiometabolic risk measures.

Foods high in whole grain may not significantly contribute to the deleterious associations previously observed between UPF intake and cardiometabolic risk factors. Consideration of their contribution to healthful dietary patterns and diet quality in the US population should be made prior to endorsement of Nova.

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Predictive validity of the Academy of Nutrition and Dietetics/American Society for Parenteral and Enteral Nutrition indicators to diagnose malnutrition tool in hospitalized adults: a cohort study.

Findings from this multihospital study confirm the predictive validity of the original or simplified AAIM tool and support its routine use for hospitalized adult patients.

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The effects of prenatal and postnatal high-dose vitamin B-12 supplementation on human milk vitamin B-12: a randomized, double-blind, placebo-controlled trial in Tanzania.

Prenatal maternal vitamin B-12 supplementation has benefits on short-term HM status, and postnatal maternal vitamin B-12 supplementation has benefits on long-term HM status.

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The impact of heat treatment of bovine milk on gastric emptying and nutrient appearance in peripheral circulation in healthy females: a randomized controlled trial comparing pasteurized and ultra-high temperature milk.

Contrary to expectations, gastric emptying was slower with UHT-M, yet, as anticipated, aminoacidaemia was greater. The larger GCV following UHT-M suggests that gastric volume may poorly predict circulating nutrient appearance from complex food matrices. Dairy heat treatment may be an effective tool to modify nutrient release by impacting digestion kinetics. Clinical trial registry (ACTRN12620000172909).

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Inflamm Bowel Dis

2'-Hydroxycinnamaldehyde Alleviates Intestinal Inflammation by Attenuating Intestinal Mucosal Barrier Damage Via Directly Inhibiting STAT3.

We present a novel finding that HCA reduces colitis severity by attenuating intestinal mucosal barrier damage via STAT3. This discovery holds promise as a potential new strategy to alleviate UC.

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AI-luminating Artificial Intelligence in Inflammatory Bowel Diseases: A Narrative Review on the Role of AI in Endoscopy, Histology, and Imaging for IBD.

Nonetheless, the available literature has inherent limitations and knowledge gaps that need to be addressed before AI can transition into a mainstream clinical tool for IBD. To better understand the potential value of integrating AI in IBD, we review the available literature to summarize our current understanding and identify gaps in knowledge to inform future investigations.

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Inflammatory Bowel Disease and Breastfeeding: A Narrative Review.

Dedicated IBD clinics can greatly support mothers during pregnancy and breastfeeding periods to enhance their knowledge, optimize their medication adherence, and improve their postpartum outcomes. This review aims to provide the most recent evidence-based literature regarding the safety of breastfeeding in women with IBD and the current recommendations about medical therapies with breastfeeding.

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TolDC Restores the Balance of Th17/Treg via Aryl Hydrocarbon Receptor to Attenuate Colitis.

Activation of AhR attenuates experimental colitis by modulating the balance of TolDCs and Th17/Treg. The AhR modulation of TolDCs may be a viable therapeutic approach for CD.

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J Crohns Colitis

Contrast enhanced endoscopic ultrasound detects early therapy response following anti-TNF-therapy in patients with ulcerative colitis.

dCEUS enables the early detection of therapy response in patients with aUC, which serves as a predictive marker for long term clinical success. Therefore, dCEUS serves as a diagnostic tool for assessing the probability of future therapy success.

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Disease acceptance, but not perceived control, is uniquely associated with inflammatory bowel disease-related disability.

Disease acceptance is strongly associated with IBD-related disability, supporting further research into disease acceptance as a treatment target.

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Pancreatology

Association of autoimmune pancreatitis and intraductal papillary mucinous neoplasm. A retrospective analysis from a tertiary care referral center.

Our data suggest that AIP represents a chronic inflammatory condition that might favor IPMN development with high-risk features. Prolonged surveillance of these patients and longitudinal studies are required to further test the association with AIP and malignant and pre-malignant conditions.

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Clinical diagnosis of psychiatric comorbidities, performance of screening tests and pattern of psychotropic medication use in patients with chronic pancreatitis.

Psychiatric comorbidities are common among CP patients and many receive psychotropic medications. Further studies are needed to evaluate the impact of these medications on CP symptoms.

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Incidence, implications and predictors of abdominal compartment syndrome in acute pancreatitis: A nationwide analysis.

Our study highlights the significant morbidity, mortality, and healthcare resource utilization associated with the concurrence of ACS in AP patients. We identified potential factors associated with ACS in AP patients. Significantly worse outcomes in ACS necessitate the need for early diagnosis, meticulous monitoring, and targeted therapeutic interventions for AP patients at risk of developing ACS.

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Intravenous Hemin, a potential heme oxygenase-1 activator, does not protect from post-ERCP acute pancreatitis in humans: Results of a randomized multicentric multinational placebo-controlled trial.

We failed to detect large improvements in PEP rate among participants at risk for PEP who received IV hemin immediately after the procedure compared to placebo.

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Natural history and growth prediction model of pancreatic serous cystic neoplasms.

SCNs typically have a similar growth rate regardless of initial size. An accurate predictive model can be used to identify rapidly growing outliers that may warrant surgical intervention, and this free model ( can be incorporated in the electronic medical record.

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Reviews&Editorials

Plenty of the editorials are available as full text through the publisher website using the provided link

Am J Clin Nutr

Untangling the uncertainty in B vitamins for stroke prevention: folic acid fortification, dosage, and their interaction?

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Inflamm Bowel Dis

Interleukin-18 Inhibition in Inflammatory Bowel Disease: A Delicate Balance.

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Miscellaneous

misc publications eg case reports, tools of the trade, images of the month, etc…

Inflamm Bowel Dis

Antibacterial Agents May Have Shifted Impacts on Inflammatory Bowel Diseases Along with Decrease in Gut Bacteria.

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Feasibility and Acceptability of Digital Behavioral Interventions Among Black and Hispanic Patients With Inflammatory Bowel Disease: A Randomized Pilot Study.

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The Long View: 2-Year Outcomes of Mirikizumab for Ulcerative Colitis.

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Liver Transpl

Primary sclerosing cholangitis and the risks of posttransplant lymphoproliferative disorder.

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Priority for kidney after liver transplantation: A safety net for all?

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Letters&Replies

Letters to the editors and authors’ replies

Inflamm Bowel Dis

Reply: Interleukin-18 Inhibition in Inflammatory Bowel Diseases: A Delicate Balance.

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Pancreatology

Comparison of treatments in patients with hyperlipidemic acute pancreatitis.

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